160693-95-8Relevant articles and documents
Syntheses of Antitumor Morphinane Alkaloids, Sinococuline and 6-epi-, 7-epi-, and 6-epi-7-epi-Sinococuline, from Sinomenine
Hitotsuyanagi, Yukio,Nishimura, Kunihiko,Ikuta, Hiroshi,Takeya, Koichi,Itokawa, Hideji
, p. 4549 - 4558 (2007/10/02)
An antitumor alkaloid, sinococuline 81), and its C-6 and/or C-7 epimeric analogs 3-5 have been synthesized from sinomenine (2).The carbonyl transposition from 9 to 8 using selenoxide chemistry proceeded in an efficient manner.Successive C-6 hydroxylation