1606972-85-3Relevant articles and documents
N-Bridged 1-deoxynojirimycin dimers as selective insect trehalase inhibitors
Cipolla, Laura,Sgambato, Antonella,Forcella, Matilde,Fusi, Paola,Parenti, Paolo,Cardona, Francesca,Bini, Davide
, p. 46 - 49 (2014)
A small set of N-bridged 1-deoxynojirimycin dimers has been synthesized and evaluated as potential inhibitors of insect trehalase from midge larvae of Chironomus riparius, porcine trehalase as the mammalian counterpart and α-amylase from human saliva. All the tested compounds (2-4) proved to be active (micromolar range activity) against insect trehalase, showing selectivity toward the insect glycosidase. No activity was observed against α-amylase.