1607-01-8

Usage

Uses

Used in Propellant Industry:
Pentaerythritol dinitrate is used as an explosive component for various types of propellants. Its high energy content and stability make it a valuable ingredient in the formulation of these products.
Used in Explosive Industry:
In the explosive industry, Pentaerythritol dinitrate is used as a key ingredient in the production of different kinds of explosives. Its high oxygen content and stability contribute to the effectiveness and reliability of these explosives.
Used in Pyrotechnic Industry:
Pentaerythritol dinitrate is utilized as a component in pyrotechnics due to its explosive properties. It plays a crucial role in the creation of various pyrotechnic effects, such as fireworks and flares.
Used in Medical Applications:
Pentaerythritol dinitrate is used as a vasodilator in the treatment of angina pectoris. It aids in the relaxation of smooth muscle cells within the blood vessels, providing relief from chest pain and improving blood flow.
However, due to its explosive nature, Pentaerythritol dinitrate is categorized as a hazardous substance. It is essential to exercise proper care in its storage and handling to prevent any accidental detonation.

InChI:InChI=1/C5H10N2O8/c8-1-5(2-9,3-14-6(10)11)4-15-7(12)13/h8-9H,1-4H2

Upstream product

• 78-11-5 Pentaerythritol tetranitrate 
• 93263-74-2 1,3-diacetoxy-2,2-bis-nitrooxymethyl-propane 
• 115-77-5 Pentaerythritol 
• 1607-17-6 pentrinitrol 

Downstream Products

• 115-77-5 Pentaerythritol 
• 1607-00-7 pentaerythrityl mononitrate 

Relevant academic research and scientific papers

Method for preparing nitro compound by using graphene to catalyze nitric oxide

The invention discloses a method for preparing a nitro compound by using graphene to catalyze nitric oxide. A graphene oxide carbon material is used for catalysis of a reaction of nitric oxide and a nitrification substrate such as an aromatic compound to prepare the nitro compound. The method is used for replacing a traditional nitric acid/sulfur acid method to prepare the nitro compound, so thatthe atom utilization rate of the reaction is increased, the energy is saved, and the emission is reduced; and the method has the characteristic of atom economy during industrial preparation of the nitro compound.

NO donors. Part 18: Bioactive metabolites of GTN and PETN-Synthesis and vasorelaxant properties

The vasodilators glyceryl trinitrate (GTN) and pentaerythrityl tetranitrate (PETN) are supposed to be degraded in vivo to the lower nitrates PETriN, PEDN, PEMN, 1,2-GDN, 1,3-GDN, 1-GMN, and 2-GMN. We synthesized these bioactive metabolites as reference compounds for pharmacokinetic studies. The use of HPLC-methods for monitoring the stepwise reduction of PETN to lower nitrates and the syntheses of the glyceryl dinitrates proved advantageous. Furthermore, we measured the vasorelaxant properties of all metabolites by performing organ bath experiments with porcine pulmonary arteries. In general, the vasodilator potency increases with the number of nitrate moieties in the compound.

Synthesis and study of organic nitrates of heterofunctional series 5. * Synthesis of 3,3-bis(hydroxymethyl)oxetane mono- and dinitrates and 2,2-bis(hydroxymethyl)propane-1,3-diol (pentaerythritol) mono- and dinitrates

New procedures were developed for the synthesis of 3,3-bis(hydroxymethyl) oxetane dinitrate (1) by O-nitration of the corresponding glycol (3) or its mononitrate (6), which were prepared by the reactions of 2,2-bis(hydroxymethyl) propane-1,3-diol (pentaerythritol) (2) mono- (4) and dinitrates (5), respectively, with alkali. A new method was devised for the synthesis of compounds 4 and 5 by the reaction of tetraol 2 with concentrated HNO 3 in dichloroethane. The structures of compounds 1 and 6 were established by X-ray diffraction analysis.

Pentaerythrite derivatives, the production and use thereof and intermediate products for the synthesis of the same

The invention relates to novel compounds derived from pentaerythrite compounds of formula (XII) and (XVI), which can be used as pharmaceutically active substances, specially in the treatment of cardiac and circulatory diseases.