1607005-57-1

Upstream product

• 112734-22-2 4-bromo-2-fluorobenzylamine 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 

Downstream Products

• 1607005-58-2 4-(tert-butyl)-N-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)benzamide 
• 1607005-19-5 4-{4-[(4-tert-butylbenzoylamino)methyl]-3-fluorophenyl}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid tert-butyl ester 
• 1607005-20-8 4-{4-[(4-tert-butylbenzoylamino)methyl]-3-fluorophenyl}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid 
• 1607005-21-9 4-tert-butyl-N-(2-fluoro-4-(6-(morpholine-4-carbonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzyl)benzamide 
• 1607005-22-0 4-{4-[(4-tert-butylbenzoylamino)methyl]-3-fluorophenyl}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide 
• 1607005-24-2 4-{4-[(4-tert-butylbenzoylamino)methyl]-3-fluorophenyl}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (2-dimethylaminoethyl)amide 

Relevant academic research and scientific papers

PYRAZOLO[3,4-b]PYRIDINE AND PYRROLO[2,3-b]PYRIDINE INHIBITORS OF BRUTON'S TYROSINE KINASE

Disclosed are pyrazolo[3,4-b]pyridine and pyrrolo[2,3-b]pyridine inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combin

HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF

The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.

INHIBITORS OF BRUTON'S TYROSINE KINASE

This application discloses compounds according to generic Formula I: wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with exc