1607015-02-0Relevant articles and documents
A synthesis of functionalized 2-imino-1,3-thiazoles from tetramethylguanidine, isothiocyanates, and 2-chloro-1,3-dicarbonyl compounds
Yavari, Issa,Malekafzali, Alaleh,Seyfi, Samereh
, p. 285 - 288 (2014)
The Hantzsch method for thiazole synthesis is modified via the reaction of 2-chloro-1,3-dicarbonyl compounds with 2-(amidosulfanylenemethyl)-1,1,3,3- tetramethylguanidines (prepared in situ from tetramethylguanidine and isothiocyanates), to afford functionalized 2-imino-1,3-thiazoles in good yields. Graphical Abstract: [Figure not available: see fulltext.]