1607015-02-0

Basic information

• Product Name: 1-(2-(4-fluorophenylimino)-3-(bis(dimethylamino)methyl)-2,3-dihydro-4-methylthiazol-5-yl)ethanone chloride
• CAS NO: 1607015-02-0
• Molecular Weight: 384.905
• Mol File: 1607015-02-0.mol

Chemical Properties

• CAS DataBase Reference: 1-(2-(4-fluorophenylimino)-3-(bis(dimethylamino)methyl)-2,3-dihydro-4-methylthiazol-5-yl)ethanone chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(4-fluorophenylimino)-3-(bis(dimethylamino)methyl)-2,3-dihydro-4-methylthiazol-5-yl)ethanone chloride(1607015-02-0)
• EPA Substance Registry System: 1-(2-(4-fluorophenylimino)-3-(bis(dimethylamino)methyl)-2,3-dihydro-4-methylthiazol-5-yl)ethanone chloride(1607015-02-0)

Safety Data

• Hazardous Substances Data: 1607015-02-0(Hazardous Substances Data)

Upstream product

• 1694-29-7 3-chloropentane-2,4-dione 
• 1544-68-9 4-fluorophenyl isothiocyanate 
• 80-70-6 N,N,N',N'-tetramethylguanidine 

Relevant articles and documents

A synthesis of functionalized 2-imino-1,3-thiazoles from tetramethylguanidine, isothiocyanates, and 2-chloro-1,3-dicarbonyl compounds

The Hantzsch method for thiazole synthesis is modified via the reaction of 2-chloro-1,3-dicarbonyl compounds with 2-(amidosulfanylenemethyl)-1,1,3,3- tetramethylguanidines (prepared in situ from tetramethylguanidine and isothiocyanates), to afford functionalized 2-imino-1,3-thiazoles in good yields. Graphical Abstract: [Figure not available: see fulltext.]