160714-27-2

Upstream product

• 160797-54-6 Methyl (2Z,4R)-4-benzyloxy-2-pentenoate 
• 160714-26-1 (1R,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-2-(1-phenylsulfanylmethyl-vinyl)-bicyclo[3.2.1]octane-1-carboxylic acid methyl ester 
• 1026868-84-7 [(1S,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-2-(1-phenylsulfanylmethyl-vinyl)-bicyclo[3.2.1]oct-1-yl]-methanol 
• 160714-25-0 (1R,2R,5R,6R,8R)-2-Acetyl-6,8-bis-methoxymethoxy-6-methyl-bicyclo[3.2.1]octane-1-carboxylic acid methyl ester 
• 160714-19-2 (1R,6R)-6-((R)-1-Benzyloxy-ethyl)-2-oxo-1-prop-2-ynyl-cyclohex-3-enecarboxylic acid methyl ester 
• 1026585-61-4 (1R,4R,5R,8R,9R,11R)-9,11-Bis-methoxymethoxy-4,9-dimethyl-3-oxa-tricyclo[6.2.1.0^1,5]undecan-2-one 
• 160714-18-1 (1R,6R)-6-((R)-1-Benzyloxy-ethyl)-2-oxo-cyclohex-3-enecarboxylic acid methyl ester 
• 160714-24-9 (1R,4R,5R,8R,9R,11R)-9,11-Dihydroxy-4,9-dimethyl-3-oxa-tricyclo[6.2.1.0^1,5]undecan-2-one 
• 160714-21-6 (3R,3aR,7R,7aR)-7-Hydroxy-3-methyl-7a-prop-2-ynyl-3a,4,7,7a-tetrahydro-3H-isobenzofuran-1-one 
• 160714-20-5 (3R,3aR,7aR)-3-Methyl-7a-prop-2-ynyl-3a,7a-dihydro-3H,4H-isobenzofuran-1,7-dione 

Downstream Products

• 1027412-57-2 (S)-6-((1R,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-1-vinyl-bicyclo[3.2.1]oct-2-yl)-1-(4-methoxy-benzyloxy)-2,2-dimethyl-5-phenylsulfanyl-hept-6-en-3-ol 
• 1026577-65-0 (E)-(S)-6-((1R,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-1-vinyl-bicyclo[3.2.1]oct-2-yl)-3-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-7-phenylsulfanyl-hept-5-en-1-ol 
• 1027509-58-5 (E)-(S)-6-((1R,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-1-vinyl-bicyclo[3.2.1]oct-2-yl)-3-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-7-phenylsulfanyl-hept-5-enal 
• 1026804-55-6 (E)-(S)-6-((1R,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-1-vinyl-bicyclo[3.2.1]oct-2-yl)-1-(4-methoxy-benzyloxy)-2,2-dimethyl-7-phenylsulfanyl-hept-5-en-3-ol 
• 1026597-83-0 {(E)-(S)-4-((1R,2R,5R,6R,8R)-6,8-Bis-methoxymethoxy-6-methyl-1-vinyl-bicyclo[3.2.1]oct-2-yl)-1-[2-(4-methoxy-benzyloxy)-1,1-dimethyl-ethyl]-5-phenylsulfanyl-pent-3-enyloxy}-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

Total Synthesis of (-)-Grayanotoxin III

Total synthesis of (-)-grayanotoxin III (3), a unique tetracyclic diterpene isolated from the leaves of various plants of the family Ericaceae, has been successfully accomplished featuring the highly stereoselective cyclization reactions induced by SmI2.