160744-54-7

Upstream product

• 87188-70-3 methyl 5-(tert-butyl)-2-methoxybenzoate 
• 73469-54-2 5-tert-butyl-2-methoxybenzoic acid 

Downstream Products

• 911060-74-7 1-(5-tert-butyl-2-methoxybenzyl)-5-chloro-1H-indole-2-carboxylic acid ethyl ester 
• 911060-75-8 1-(5-tert-butyl-2-methoxybenzyl)-5-chloro-1H-indole-2-carboxylic acid 
• 911060-73-6 2-(bromomethyl)-4-(tert-butyl)-1-methoxybenzene 

Relevant academic research and scientific papers

Substituted Pyrrolidines and Methods of Use

The invention discloses compounds of Formula (I) wherein R1, R2, R2A, R3, R3A, R4, and R5 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.

1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES

The present invention relates to i-benzylindole-2-carboxamide derivatives of formula I, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 1-benzylindole-2-carboxamide deriva