160746-91-8Relevant academic research and scientific papers
Synthesis of GABA-Analogous Spirocyclic Amino Acids, 4. N-Benzyl-2-azaspirononane-6-carboxylates
Hollauf, Gabriele,Urban, Ernst
, p. 2295 - 2308 (2007/10/02)
Alkylation of 2-oxocyclopentanecarboxylate (4) with 1,2-dibromoethane and reaction with benzylamine gave 2-azaspirononane-1,6-dione (7).After selective reduction of 7 at the lactam function, we obtained 2-azaspirononan-6-one (9) which was treate
