1607474-29-2

Basic information

• Product Name: trans-4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexylamine
• Synonyms: trans-4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexylamine
• CAS NO: 1607474-29-2
• Molecular Weight: 403.611
• Mol File: 1607474-29-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexylamine(1607474-29-2)
• EPA Substance Registry System: trans-4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexylamine(1607474-29-2)

Safety Data

• Hazardous Substances Data: 1607474-29-2(Hazardous Substances Data)

Upstream product

• 1607474-24-7 2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-ol 
• 62462-05-9 methyl 5-methoxy-3-oxopentanoate 
• 1607474-28-1 trans-[4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexyl]carbamic acid tert-butyl ester 
• 1607474-25-8 2-tert-butyl-4-chloro-6-(2-methoxyethyl)pyrimidine 

Downstream Products

• 1607474-54-3 trans-N-[4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexyl]formamide 
• 1607474-59-8 trans-N-[4-(2-{4-[2-tert-butyl-6-(2-hydroxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexyl]acetamide 
• 1607474-27-0 trans-N-[4-(2-{4-[2-tert-butyl-6-(2-methoxyethyl)pyrimidin-4-yl]piperazin-1-yl}ethyl)cyclohexyl]acetamide 

Relevant articles and documents

ACYLAMINOCYCLOALKYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF DOPAMINE D3 RECEPTOR

The present invention relates to novel acylaminocycloalkyl compounds, in particular to the compounds of the formula (I) as described herein and to their salts and N-oxides. The compounds possess valuable therapeutic properties and are suitable, in particular, for treating diseases that respond to modulation of the dopamine D3 receptor. In formula (I), the variables have the following meanings: m is 1 or 2, n is 1 or 2, A is selected from the group consisting of CH2, CH2CH2, CHFCH2 and CF2CH2, R1 is hydrogen or C1-C3-alkyl, R2 is selected from the group consisting of hydrogen, and fluorine, R3a is selected from the group consisting of hydrogen and methyl, R3b is selected from the group consisting of hydrogen and methyl, R4 is branched C4-C6 alkyl or branched fluorinated C4-C6 alkyl, and R5 is an oxygen containing radical such as C1-C2-alkoxy-C1-C4-alkyl, fluorinated C1-C2-alkoxy-C1-C4-alkyl, hydroxy-C1-C4-alkyl, fluorinated hydroxy-C1-C4-alkyl, oxetanyl, fluorinated oxetanyl, oxolanyl, fluorinated oxolanyl, C3-C5 cycloalkyl, fluorinated C3-C5 cycloalkyl, C3-C5 cycloalkoxy-C1-C4-alkyl and fluorinated C3-C5 cycloalkoxy-C1-C4-alkyl.