160785-01-3

Basic information

• Product Name: 3-(3-chloro-phenyl)-3-methyl-2-oxo-butyric acid
• CAS NO: 160785-01-3
• Molecular Weight: 226.66
• Mol File: 160785-01-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-chloro-phenyl)-3-methyl-2-oxo-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-chloro-phenyl)-3-methyl-2-oxo-butyric acid(160785-01-3)
• EPA Substance Registry System: 3-(3-chloro-phenyl)-3-methyl-2-oxo-butyric acid(160785-01-3)

Safety Data

• Hazardous Substances Data: 160785-01-3(Hazardous Substances Data)

Upstream product

• 96406-06-3 3-(3-Chlorphenyl)-2-oxopropansaeure 
• 74-88-4 methyl iodide 

Downstream Products

• 676631-37-1 (E)-(S)-4-({(S)-2-[(R)-3-(3-Chloro-phenyl)-3-methyl-2-methylamino-butyrylamino]-3,3-dimethyl-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid ethyl ester 
• 676631-63-3 (E)-(S)-4-({(S)-2-[(S)-3-(3-Chloro-phenyl)-3-methyl-2-methylamino-butyrylamino]-3,3-dimethyl-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid ethyl ester 
• 676626-71-4 3-(3-chloro-phenyl)-3-methyl-2-methylamino-butyric acid 
• 676631-65-5 (E)-(S)-4-({(S)-2-[(S)-3-(3-Chloro-phenyl)-3-methyl-2-methylamino-butyrylamino]-3,3-dimethyl-butyryl}-methyl-amino)-2,5-dimethyl-hex-2-enoic acid 

Relevant articles and documents

Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: Modification of the a segment

Analogs of HTI-286 (1), containing various aromatic rings in the A segment, were synthesized as potential inhibitors of tubulin polymerization, and the structure-activity relationships related to stereo- and regio-chemical effects of substituents on the a