1608-45-3 Usage
Family
Diiodobenzene family
Structure
Chlorine atom and two iodine atoms attached to a benzene ring
Usage
Primarily used in organic synthesis
Applications
Production of pharmaceuticals, agrochemicals, and other fine chemicals
Reactions
Undergoes substitution and coupling reactions
Versatility
Acts as a versatile building block in chemical synthesis
Role
Serves as a starting material or intermediate in manufacturing various industrial and scientific products
Interest
Of interest to researchers and industries involved in organic chemistry and materials science
Check Digit Verification of cas no
The CAS Registry Mumber 1608-45-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,0 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1608-45:
(6*1)+(5*6)+(4*0)+(3*8)+(2*4)+(1*5)=73
73 % 10 = 3
So 1608-45-3 is a valid CAS Registry Number.
1608-45-3Relevant articles and documents
Preparation of N-Substituted Phthalimides by Palladium-Catalyzed Carbonylation and Coupling of o-Dihalo Aromatics and Primary Amines
Perry, Robert J.,Turner, S. Richard
, p. 6573 - 6579 (2007/10/02)
A novel method for the formation of N-substituted phthalimides is described which is based on the palladium-catalyzed carbonylation and coupling of o-dihalo aromatics and primary amines.Optimal conditions established for the reaction using o-diiodobenzene and aniline were DMAc (0.2 M), 115 deg C, 90 psi of CO, 3 percent PdCl2L2, and 2.4 equiv of DBU.This process is tolerant of a wide variety of functional groups and gives good yields of the desired products.Variables such as temperature, catalyst type and loading, CO pressure, solvent, and base were examined to optimize this reaction.The reaction of aniline with 1,2-dibromocyclopentene under similar conditions gave a variety of products.
