Diethyl β-fluoro-α-oxo-glutarate, also known as DEFOX, is a chemical compound with the molecular formula C8H11FO4. It is a colorless to pale yellow liquid that is soluble in water and organic solvents. DEFOX is a potent inhibitor of the enzyme enolase, which plays a crucial role in the glycolytic pathway of cells. By inhibiting enolase, DEFOX disrupts the energy metabolism of cells, leading to cell death. This property makes it a potential therapeutic agent for the treatment of certain diseases, such as cancer, where it can selectively target cancer cells while sparing healthy cells. The compound is also used in research to study the role of enolase in various biological processes. Due to its potential applications, DEFOX is a subject of ongoing research in the fields of medicine and biochemistry.
The CAS Registry Mumber 1608-56-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,0 and 8 respectively; the second part has 2 digits, 5 and 6 respectively. Calculate Digit Verification of CAS Registry Number 1608-56: (6*1)+(5*6)+(4*0)+(3*8)+(2*5)+(1*6)=76 76 % 10 = 6 So 1608-56-6 is a valid CAS Registry Number.