160836-01-1Relevant academic research and scientific papers
Role of a Protected Vicinal Diol Controller in Intramolecular Cycloaddition Reactions of Chiral Acyclic Alkenyl Nitrones: Syntheses of Enantiomerically Pure Tetrasubstituted Cyclobutylamines
Saito, Seiki,Ishikawa, Teruhiko,Moriwake, Toshio
, p. 4375 - 4377 (2007/10/02)
Intramolecular cycloaddition reactions of C5-chain acyclic alkenyl nitrones such as N-benzylamine N-oxide and its C(5)-substituted derivatives lead to fused isoxazolidines (bicyclo framework) with very high diastereomeric excess.These isoxazolidines can readily be converted to optically active tetrasubstituted cyclobutylamines.
