1608485-24-0

Basic information

• Product Name: 1,4-di[α-L-fucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl-1,2,3-triazol-4-ylmethyloxy]benzene
• Synonyms: 1,4-di[α-L-fucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl-1,2,3-triazol-4-ylmethyloxy]benzene
• CAS NO: 1608485-24-0
• Molecular Weight: 1213.12
• Mol File: 1608485-24-0.mol

Chemical Properties

• CAS DataBase Reference: 1,4-di[α-L-fucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl-1,2,3-triazol-4-ylmethyloxy]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-di[α-L-fucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl-1,2,3-triazol-4-ylmethyloxy]benzene(1608485-24-0)
• EPA Substance Registry System: 1,4-di[α-L-fucopyranosyl-(1→2)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl-1,2,3-triazol-4-ylmethyloxy]benzene(1608485-24-0)

Safety Data

• Hazardous Substances Data: 1608485-24-0(Hazardous Substances Data)

Relevant articles and documents

Combining glycocluster synthesis with protein engineering: An approach to probe into the significance of linker length in a tandem-repeat-type lectin (galectin-4)

Complementarity in lectin-glycan interactions in situ is assumed to involve spatial features in both the lectin and the glycan, giving a functional meaning to structural aspects of the lectin beyond its carbohydrate-binding site. In combining protein engineering with glycocluster synthesis, it is shown that the natural linker length of a tandem-repeat-type human lectin (galectin-4) determines binding properties in two binding assays (using surface-presented glycoprotein and cell surface assays). The types of glycocluster tested included bivalent lactosides based on tertiary amides of terephthalic, isophthalic, 2,6-naphthalic and oxalic acids as well as bivalent H(type 2) trisaccharides grafted on secondary/tertiary terephthalamides and two triazole-linker- containing cores. The presented data reveal a marked change in susceptibility to the test compounds when turning the tandem-repeat-type to a proto-type-like display. The testing of glycoclusters is suggested as a general strategy to help to delineate the significance of distinct structural features of lectins beyond their contact sites to the glycan.