1608489-90-2Relevant articles and documents
Synthesis of antimicrobial cyclodextrins bearing polyarylamino and polyalkylamino groups via click chemistry for bacterial membrane disruption
Yamamura, Hatsuo,Sugiyama, Yuuki,Murata, Kensuke,Yokoi, Takanori,Kurata, Ryuji,Miyagawa, Atsushi,Sakamoto, Kenji,Komagoe, Keiko,Inoue, Tsuyoshi,Katsu, Takashi
supporting information, p. 5444 - 5446 (2014/05/20)
Cyclodextrin derivatives are synthesized as membrane-disrupting agents via a microwave-assisted Huisgen reaction. Their ability to permeabilize bacterial membranes depends on the amino substituents and an appropriate balance of hydrophobicity and hydrophilicity, thus enabling the preparation of derivatives with selective toxicity against bacteria. This journal is the Partner Organisations 2014.