1608496-96-3

Basic information

• Product Name: C₂₄H₂₇ClN₂O₄
• Synonyms: C₂₄H₂₇ClN₂O₄
• CAS NO: 1608496-96-3
• Molecular Weight: 442.942
• Mol File: 1608496-96-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₇ClN₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₇ClN₂O₄(1608496-96-3)
• EPA Substance Registry System: C₂₄H₂₇ClN₂O₄(1608496-96-3)

Safety Data

• Hazardous Substances Data: 1608496-96-3(Hazardous Substances Data)

Upstream product

• 5000-66-8 2-chlorophenacyl bromide 
• 72702-57-9 2-Bromo-1-(2-chlorophenyl)ethan-1-ol 
• 1613220-26-0 C₂₄H₂₈BrClN₂O₄ 

Downstream Products

• 1608496-87-2 C₁₉H₁₉ClN₂O₂ 

Relevant articles and documents

Lactam and oxazolidinone derived potent 5-hydroxytryptamine 6 receptor antagonists

Lactam and oxazolidinone derived potent 5-hydroxytryptamine 6 (5-HT 6) receptor antagonists have been disclosed. One potent member from the lactam series, racemic compound 14 (Ki of 2.6 nM in binding assay, IC50 of 15 nM in functional cAMP antagonism assay) was separated into corresponding enantiomers that displayed the effect of chirality on binding potency (Ki of 1.6 nM and 3000 nM, respectively). The potent enantiomer displayed an IC50 of 8 nM in cAMP antagonism assay, selectivity against a number of family members as well as brain permeability in rats after 6 h post oral administration.