1608889-64-0Relevant academic research and scientific papers
Improving the solubility of lenalidomide via cocrystals
Song, Jia-Xi,Yan, Yan,Yao, Jia,Chen, Jia-Mei,Lu, Tong-Bu
, p. 3069 - 3077 (2014)
An anticancer drug, lenalidomide, has low oral bioavailability (below 33%) due to its poor solubility in water. To improve its solubility, three cocrystals of lenalidomide with urea (1) and 3,5-dihydroxybenzoic acid (2, 3) were prepared. The structures of
