1608889-96-8Relevant academic research and scientific papers
Conjugation of Hydroxytyrosol with Other Natural Phenolic Fragments: From Waste to Antioxidants and Antitumour Compounds
Tassano, Erika,Alama, Angela,Basso, Andrea,Dondo, Giancarlo,Galatini, Andrea,Riva, Renata,Banfi, Luca
, p. 6710 - 6726 (2015)
Hydroxytyrosol, a natural polyphenol that can be extracted from olive mill waste waters, was converted into a series of more complex and lipophilic analogues by conjugation with other naturally derived (poly)phenolic fragments. Ether and triazole linkers were employed. A small library of compounds was prepared, stressing step economy and operational simplicity. Some of these substances were proven to have activity equal or superior to that of the parent hydroxytyrosol in radical scavenging assays as well as in cytotoxicity tests against tumour cells.
A magnetoclick imidazolidinone nanocatalyst for asymmetric 1,3-dipolar cycloadditions
Pagoti, Sreenivasarao,Dutta, Debasish,Dash, Jyotirmayee
supporting information, p. 3532 - 3538 (2014/01/06)
A 1,3-dipolar azide-alkyne cycloaddition has been used to prepare a magnetic nanoparticle immobilized MacMillan catalyst that catalyzes the enantioselective 1,3-dipolar cycloaddition between nitrones and α,β-unsaturated aldehydes. The catalyst can be recovered and recycled for five consecutive runs without any significant loss in yields and diastereo- and enantioselectivities of the isoxazolidines. Copyright
