16089-70-6

Usage

Uses

Used in Agricultural Industry:
Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide is used as a herbicide for controlling grass and broadleaf weeds in a variety of crops. It is particularly favored for its application in rice paddies and other aquatic environments due to its low water solubility, which minimizes the risk of runoff into water sources. Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide's low toxicity to non-target organisms and minimal impact on soil microbiology make it a suitable choice for weed management in agricultural settings.
However, it is crucial to handle Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide with caution, as it can pose health risks if ingested, inhaled, or if it comes into contact with the skin or eyes. Proper safety measures should be taken to ensure the safe and effective use of this herbicide in agricultural practices.

InChI:InChI=1/C9H8N2O/c1-11(12)7-9-4-2-8(6-10)3-5-9/h2-5,7H,1H3/b11-7+

Upstream product

• 75-52-5 nitromethane 
• 105-07-7 4-cyanobenzaldehyde 
• 4229-44-1 N-methylhydroxyamine hydrochloride 
• 79069-32-2 phenyl(phenylethynyl)iodonium tosylate 

Downstream Products

• 123466-44-4 3-(p-cyanophenyl)-5-phenyl-2,3-dihydroisoxazol-4-yl(phenyl)iodonium toluene-p-sulphonate 
• 105-07-7 4-cyanobenzaldehyde 
• 1542213-01-3 C₉H₈N₂O 
• 1385717-25-8 C₃₅H₂₈N₄O₄ 

Relevant academic research and scientific papers

Cooperative Multifunctional Catalysts for Nitrone Synthesis: Platinum Nanoclusters in Amine-Functionalized Metal–Organic Frameworks

Nitrones are key intermediates in organic synthesis and the pharmaceutical industry. The heterogeneous synthesis of nitrones with multifunctional catalysts is extremely attractive but rarely explored. Herein, we report ultrasmall platinum nanoclusters (PtNCs) encapsulated in amine-functionalized Zr metal–organic framework (MOF), UiO-66-NH2 (Pt@UiO-66-NH2) as a multifunctional catalyst in the one-pot tandem synthesis of nitrones. By virtue of the cooperative interplay among the selective hydrogenation activity provided by the ultrasmall PtNCs and Lewis acidity/basicity/nanoconfinement endowed by UiO-66-NH2, Pt@UiO-66-NH2 exhibits remarkable activity and selectivity, in comparison to Pt/carbon, Pt@UiO-66, and Pd@UiO-66-NH2. Pt@UiO-66-NH2 also outperforms Pt nanoparticles supported on the external surface of the same MOF (Pt/UiO-66-NH2). To our knowledge, this work demonstrates the first examples of one-pot synthesis of nitrones using recyclable multifunctional heterogeneous catalysts.

Solvent-free synthesis of nitrones in a ball-mill

Various C-aryl and C-alkyl-nitrones were synthesized within 0.5-2 h via condensation of an equimolar amount of aldehydes and N-substituted-hydroxylamines under solvent-free conditions in?a ball-mill apparatus. Reactions can be performed without the need of excluding air and moisture and yields the expected products with no need for further purification. The study has been complemented by Differential Scanning Calorimetry (DSC) and solid-state 13C MAS nuclear magnetic resonance experiments. We have also studied the temperature profile during the reaction. A comparative study with the corresponding solvent-free microwave activated reaction showed the superiority of the ball-milling method; 31 examples are described, including the synthesis of the anti-aging agent C-phenyl-N-tert-butyl nitrone (PBN) and one of its analogues C-2-pyridyl-N-tert-butylnitrone (2-PyBN).

Cyclic carbamates and isoxazolidines as IIb/IIIa antagonists

The present invention relates generally to cyclic carbamates and isoxazolidines or Formula (I) or their pharmaceutically acceptable salts thereof, which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, to pharma

Cyclic carbamates and isoxazolidines as IIb/IIIa antagonists

STR1 This invention relates generally to cyclic carbamates and hydroxylamines which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, to pharmaceutical compositions containing such compounds, processes for prepar

Platelet glycoprotein IIb/IIIa receptor antagonists derived from isoxazolidines

A series of isoxazolidines has been synthesized as mimetics of the RGD sequence and was evaluated as antagonists of the platelet glycoprotein IIb/IIIa receptor. These compounds were shown to be highly potent GPIIb/IIIa antagonists, exhibiting submicromolar potencies.

Chromium and Tungsten Pentacarbonyl Groups as Reactivity and Selectivity Auxiliaries in Cycloaddition of Alkynyl Fischer Carbene Complexes with N-Alkyl Nitrones

Alkynyl Fischer carbene complexes were found to undergo chemoselective, regioselective, and rate-enhanced 1,3-dipolar cycloaddition with nitrones to give 2,3-dihydroisoxazole carbene complexes in excellent yields.These alkynyl complexes can serve as synth

Reactivity of Arylethynyl(phenyl)iodonium Salts Towards some 1,3-Dipoles. X-Ray Molecular Structure of 3-Mesityl-5-phenylisoxazol-4-yl(phenyl)iodonium Toluene-p-sulphonate

Three arylethynyl(phenyl)iodonium salts reacted as 1,3-dipolarophiles with two nitrile oxides to afford phenyl(substituted isoxazolyl)iodonium salts; these gave iodoisoxazoles on reaction with nucleophiles.Phenyl(phenylethynyl)iodonium toluene-p-sulphonate reacted in the same way with nitrones but the resulting phenyl(substituted isoxazolinyl)iodonium salts, with one exeption, were difficult to isolate because of ready hydrolysis.The crystal structure of 3-mesityl-5-phenylisoxazol-4-yl(phenyl)iodonium toluene-p-sulphonate has been determined.