16089-70-6

Basic information

• Product Name: Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide
• Synonyms: Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide
• CAS NO: 16089-70-6
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17
• Mol File: 16089-70-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 332.6°C at 760 mmHg
• Flash Point: 155°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.000144mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide(16089-70-6)
• EPA Substance Registry System: Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide(16089-70-6)

Safety Data

• Hazardous Substances Data: 16089-70-6(Hazardous Substances Data)

Usage

General Description

Benzonitrile,4-[(methylimino)methyl]-N(4)-oxide, also known as carbetamide, is a chemical compound used as a herbicide to control grass and broadleaf weeds in a variety of crops. It works by inhibiting the growth of weeds through interference with their hormone systems. Carbetamide is primarily used in rice paddies and other aquatic environments due to its low water solubility and potential for runoff into water sources. Additionally, it has shown to have low toxicity to non-target organisms and minimal impact on soil microbiology, making it a favorable choice for weed control in agricultural settings. However, it is important to handle this chemical with care, as it can be harmful if ingested or inhaled, and skin and eye contact should be avoided.

InChI:InChI=1/C9H8N2O/c1-11(12)7-9-4-2-8(6-10)3-5-9/h2-5,7H,1H3/b11-7+

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 4229-44-1 N-methylhydroxyamine hydrochloride 
• 75-52-5 nitromethane 
• 79069-32-2 phenyl(phenylethynyl)iodonium tosylate 

Downstream Products

• 123466-44-4 3-(p-cyanophenyl)-5-phenyl-2,3-dihydroisoxazol-4-yl(phenyl)iodonium toluene-p-sulphonate 
• 105-07-7 4-cyanobenzaldehyde 
• 1542213-01-3 C₉H₈N₂O 
• 1385717-25-8 C₃₅H₂₈N₄O₄ 

Relevant articles and documents

Cooperative Multifunctional Catalysts for Nitrone Synthesis: Platinum Nanoclusters in Amine-Functionalized Metal–Organic Frameworks

Nitrones are key intermediates in organic synthesis and the pharmaceutical industry. The heterogeneous synthesis of nitrones with multifunctional catalysts is extremely attractive but rarely explored. Herein, we report ultrasmall platinum nanoclusters (PtNCs) encapsulated in amine-functionalized Zr metal–organic framework (MOF), UiO-66-NH2 (Pt@UiO-66-NH2) as a multifunctional catalyst in the one-pot tandem synthesis of nitrones. By virtue of the cooperative interplay among the selective hydrogenation activity provided by the ultrasmall PtNCs and Lewis acidity/basicity/nanoconfinement endowed by UiO-66-NH2, Pt@UiO-66-NH2 exhibits remarkable activity and selectivity, in comparison to Pt/carbon, Pt@UiO-66, and Pd@UiO-66-NH2. Pt@UiO-66-NH2 also outperforms Pt nanoparticles supported on the external surface of the same MOF (Pt/UiO-66-NH2). To our knowledge, this work demonstrates the first examples of one-pot synthesis of nitrones using recyclable multifunctional heterogeneous catalysts.

Cyclic carbamates and isoxazolidines as IIb/IIIa antagonists

The present invention relates generally to cyclic carbamates and isoxazolidines or Formula (I) or their pharmaceutically acceptable salts thereof, which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, to pharma

Platelet glycoprotein IIb/IIIa receptor antagonists derived from isoxazolidines

A series of isoxazolidines has been synthesized as mimetics of the RGD sequence and was evaluated as antagonists of the platelet glycoprotein IIb/IIIa receptor. These compounds were shown to be highly potent GPIIb/IIIa antagonists, exhibiting submicromolar potencies.