1609006-65-6

Basic information

• Product Name: 2-amino-5-iodo-3-methylbenzohydrazide
• Synonyms: 2-amino-5-iodo-3-methylbenzohydrazide
• CAS NO: 1609006-65-6
• Molecular Weight: 291.091
• Mol File: 1609006-65-6.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-5-iodo-3-methylbenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-iodo-3-methylbenzohydrazide(1609006-65-6)
• EPA Substance Registry System: 2-amino-5-iodo-3-methylbenzohydrazide(1609006-65-6)

Safety Data

• Hazardous Substances Data: 1609006-65-6(Hazardous Substances Data)

Upstream product

• 913194-96-4 6-iodo-8-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 
• 108857-24-5 2-amino-5-iodo-3-methylbenzoic acid 

Downstream Products

• 1609006-83-8 methyl 5-(2-amino-5-iodo-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609007-00-2 ethyl 5-(2-amino-5-iodo-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-96-3 methyl 5-(2-(3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamido)-5-iodo-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-97-4 ethyl 5-(2-(3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamido)-5-iodo-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-72-5 2-amino-5-iodo-3-methyl-N'-(propan-2-ylidene)benzohydrazide 

Relevant articles and documents

Synthesis and insecticidal activity study of novel anthranilic diamides analogs containing a diacylhydrazine bridge as effective Ca2+ modulators

Anthranilic diamides is a class of insecticides target at ryanodine receptors (RyRs). To discover potent insecticides targeting at RyRs, a series of novel anthranilic diamides with a diacylhydrazine bridge were designed and synthesized. Their insecticidal activities were evaluated and a preliminary structure-activity relationship (SAR) was summarized. In particular, compound 5g exhibited good lethality against oriental armyworm (Mythimna separata) at a concentration of 5?mg/L. The calcium imaging experimental results indicated that the compound 5g can serve as effective insect Ca2+ level modulators by disrupting the cellular calcium homeostasis in Mythimna separata (Walker) and Spodoptera exigua (Hübner), which probably activated the RyRs on the ER membrane.

Synthesis and biological activities of 2,3-dihydro-1,3,4-oxadiazole compounds and its derivatives as potential activator of ryanodine receptors

A series of novel 2,3-dihydro-1,3,4-oxadiazoles containing N-pyridylpyrazole carboxamides moieties were obtained by applying a new synthetic route. Their insecticidal tests against oriental armyworm (Mythimna separata) and diamondback moth (Plutella xylostella) indicated that most of the compounds showed moderate to excellent activities at the testing concentrations. In particular, compound 6a showed 40% larvicidal activities against oriental armyworm at 1 mg/L, while 7a against diamondback was 100% at 0.01 mg/L. Calcium imaging results demonstrated that 6a, 6d and 7a stimulated a transient elevation in [Ca2+]i in the absence of external calcium after the central neurons dye loading with fluo-3 AM, implying that these novel compounds were potential activators of the ligand-gated calcium channel on the endoplasmic reticulum.