1609076-06-3Relevant academic research and scientific papers
A facile method for the synthesis of hydrazine-4-oxothiazolidine and imino-5-oxothiadiazine derivatives from 1,4-disubstituted thiosemicarbazides
Hassan, Alaa A.,Aly, Ashraf A.,Bedair, Tarek I. M.,Brown, Alan B.,El-Emary, Talaat I.
, p. 44 - 49 (2014/02/14)
1,4-Disubstituted thiosemicarbazides reacted with dimethyl acetylenedicarboxylate with formation of (2-hydrazono-4-oxothiazolidin-5- ylidene)acetates and, in one case, a (2-imino-1,3,4-thiadiazin-5-on-6-ylidene) acetate. Several mechanistic options involving nucleophilic interaction are presented. The structures of all newly synthesized compounds were identified by 1H NMR, 13C NMR, COSY, HMQC and HMBC spectral data.
