160911-42-2 Usage
General Description
Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI) is a chemical compound with the molecular formula C8H5N3O2. It is a heterocyclic compound containing both imidazole and pyridazine rings, making it an important structure for medicinal chemistry and drug development. Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI) has been studied for its potential pharmaceutical properties, particularly as an inhibitor of certain biological processes. Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI) has shown potential as a therapeutic agent for a range of conditions, including cancer and autoimmune diseases. Its versatile structure and potential biological activity make it an interesting target for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 160911-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,9,1 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160911-42:
(8*1)+(7*6)+(6*0)+(5*9)+(4*1)+(3*1)+(2*4)+(1*2)=112
112 % 10 = 2
So 160911-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5N3O2/c11-7(12)5-4-10-6(9-5)2-1-3-8-10/h1-4H,(H,11,12)
160911-42-2Relevant articles and documents
Research on heterocyclic compounds. XXXVIII. Synthesis and pharmacological activity of imidazo[1,2-b]pyridazine-2-carboxylic derivatives
Luraschi,Arena,Sacchi,Laneri,Abignente,Avallone,D'Amico,Berrino,Rossi
, p. 213 - 217 (2007/10/03)
A series of imidazo[1,2-b]pyridazine-2-carboxylic acids, esters and amides was synthesized and tested for antiinflammatory, analgesic and ulcerogenic activities. The ethyl esters were prepared by cyclocondensation of some 3-aminopyridazines with ethyl bromopyruvate, followed by hydrolysis or ammonolysis in order to obtain the corresponding acids and amides. The inhibitory activity on the carrageenaninduced edema in the rat paw and on writhes induced by acetic acid in mice was evaluated, as well as the ulcerogenic action on the rat gastric mucosa. The pharmacological activity was discussed in terms of structure-activity relationships. In particular, the analgestic activity shown by these carboxylic derivatives was compared with that found in other series of imidazo[1,2-b]pyridazine analogues previously examined.
