1609168-45-7Relevant academic research and scientific papers
Design and synthesis of new vancomycin derivatives
Gu, Wen,Chen, Bei,Ge, Min
, p. 2305 - 2308 (2014)
A set of vancomycin derivatives with lipid chain attached via a glyceric acid linker was designed and synthesized. A concise synthesis towards these derivatives was developed and the IC50s of these new lipoglycopeptides were tested. Some of them showed very potent activity against both vancomycin sensitive and resistant strains.
