1609180-34-8

Basic information

• Product Name: C₂₁H₁₈N₃O⁽¹⁺⁾*Cl^(1-)
• CAS NO: 1609180-34-8
• Molecular Weight: 363.846
• Mol File: 1609180-34-8.mol

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₈N₃O⁽¹⁺⁾*Cl^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₈N₃O⁽¹⁺⁾*Cl^(1-)(1609180-34-8)
• EPA Substance Registry System: C₂₁H₁₈N₃O⁽¹⁺⁾*Cl^(1-)(1609180-34-8)

Safety Data

• Hazardous Substances Data: 1609180-34-8(Hazardous Substances Data)

Upstream product

• 92961-15-4 3-phenylimidazo[1,2-a]pyridine 
• 587-65-5 N-chloroacetyl-aniline 

Relevant articles and documents

Rational design of ligand precursors to prepare abnormal (Mesoionic) and normal carbene complexes and zwitterionic CX-type palladacycles (X = C, N)

The preparation of a series of ligand precursors that feature imidazo[1,2-a]pyridine and amido functional groups is reported. The reactions between the new ligand precursors, pyridine, and palladium acetate in DMF afforded monodentate PdII abno

Rational design of ligand precursors to prepare abnormal (mesoionic) and normal carbene complexes and zwitterionic CX-type palladacycles (X = C, N)

The preparation of a series of ligand precursors that feature imidazo[1,2-a]pyridine and amido functional groups is reported. The reactions between the new ligand precursors, pyridine, and palladium acetate in DMF afforded monodentate PdII abnormal (mesoionic) carbene complexes. An isomeric PdII normal carbene complex with a formally identical steric environment to that of the abnormal carbene counterpart was also prepared. The isomeric pairs were characterized by X-ray structural studies. Under different complexation conditions, in which PdCl2 was employed as metal precursor, a zwitterionic CC-type palladacycle formed by the C-H activation at the ortho-N-phenyl and methylene carbon atoms was obtained. The use of a similar ligand precursor with an NH instead of an NMe group produced a zwitterionic palladalactam complex. In contrast to the previous work in the literature, owing to the rigidity of the fused heterocyclic ring, the palladalactam complex did not undergo intramolecular proton transfer through the coordinated N atom. Overall, we demonstrated that proper modification of the structures of ligand precursors and complexation conditions allowed us to obtain a full range of intriguing PdII complexes including normal and abnormal carbene complexes, and zwitterionic palladalactam and CC-type palladacycles by means of A-H bond (A = N, C) activations. Rational modification of the structures of ligand precursors and complexation conditions to obtain a full range of intriguing PdII complexes including abnormal (mesoionic) and normal carbene complexes, and zwitterionic palladalactam and CC-type palladacycles by means of A-H bond (A = N, C) activations is described. Copyright

Direct C-H arylations of unactivated arenes catalyzed by amido-functionalized imidazolium salts

The synthesis of biaryls from unactivated arenes and a broad range of aryl bromides and chlorides via the direct C-H functionalization can be efficiently performed with the aid of amido-functionalized imidazolium salts as organocatalysts. This method avoids the use of toxic transition metal catalysts and organometallic reagents.