1609205-24-4

Upstream product

• 941-69-5 N-phenyl-maleimide 
• 931-53-3 Cyclohexyl isocyanide 
• 1415665-21-2 methyl 2-(6-chloro-4-oxo-4H-chromen-3-yl)-2-oxoacetate 

Relevant academic research and scientific papers

Synthesis of 4-aminoxanthones by an uncatalyzed, multicomponent reaction

The synthesis of xanthones via a multicomponent reaction of isocyanides is described for the first time. In this one-pot process, a tandem [4+1] plus [4+2] cycloaddition leads to polysubstituted 4-aminoxanthones in excellent to quantitative yields at room temperature in a non-catalyzed reaction.

Tandem synthesis of 4-aminoxanthones is controlled by a water-assisted tautomerization: a general straightforward reaction

Aminoxanthones constitute a group of therapeutically promising compounds that so far have been synthetically challenging. Here, we report the synthesis of both aminodihydroxanthones and fully aromatized aminoxanthones by an easy to perform, one-step multi