1609388-03-5

Basic information

• Product Name: C₂₃H₂₅NO₉S
• CAS NO: 1609388-03-5
• Molecular Weight: 491.519
• Mol File: 1609388-03-5.mol

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₅NO₉S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₅NO₉S(1609388-03-5)
• EPA Substance Registry System: C₂₃H₂₅NO₉S(1609388-03-5)

Safety Data

• Hazardous Substances Data: 1609388-03-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1609388-07-9 C₁₈H₁₇NO₇S 
• 1609387-42-9 C₁₇H₁₅NO₆S 

Relevant articles and documents

Enantioselective intramolecular AZA-spiroannulation onto benzofurans using chiral rhodium catalysis

The development of efficient and enantioselective intramolecular aza-spiroannulation onto benzofurans using chiral rhodium catalysis is described. The optimized reaction conditions [Rh2(S-TCPTAD) 4 (3 mol %), PhIO (1.6 equiv), MeOH (10 equiv) in PhCF3, 0°C] brought about oxidative aza-spiroannulation of 3-(carbamoylmethyl) benzofuran (3) resulting in (2R,3S)-2-methoxy-2H-spiro- [benzofuran-3,4′- oxazolidin]-2′-one (15a) in 69% yield with 86% ee, the absolute structure of which was determined by a combination of X-ray crystallography and vibrational circular dichroism (VCD) spectroscopy. The reaction is applicable to the asymmetric construction of various 2,3-dihydrobenzofuran derivatives bearing a nitrogen-containing tetrasubstituted carbon stereocenter at C3 (up to 92% ee).