1609533-99-4

Basic information

• Product Name: (2Z)-(4S)-4-benzyloxy-2-[(E)-5-hydroxy-4-methylpent-3-enyl]octa-2,7-dienenitrile
• Synonyms: (2Z)-(4S)-4-benzyloxy-2-[(E)-5-hydroxy-4-methylpent-3-enyl]octa-2,7-dienenitrile
• CAS NO: 1609533-99-4
• Molecular Weight: 325.451
• Mol File: 1609533-99-4.mol

Chemical Properties

• CAS DataBase Reference: (2Z)-(4S)-4-benzyloxy-2-[(E)-5-hydroxy-4-methylpent-3-enyl]octa-2,7-dienenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-(4S)-4-benzyloxy-2-[(E)-5-hydroxy-4-methylpent-3-enyl]octa-2,7-dienenitrile(1609533-99-4)
• EPA Substance Registry System: (2Z)-(4S)-4-benzyloxy-2-[(E)-5-hydroxy-4-methylpent-3-enyl]octa-2,7-dienenitrile(1609533-99-4)

Safety Data

• Hazardous Substances Data: 1609533-99-4(Hazardous Substances Data)

Upstream product

• 113730-85-1 (S)-1-((R)-1,4-dioxaspiro[4.5]decan-2-yl)pent-4-en-1-ol 
• 1554519-04-8 (2R,3S)-3-(benzyloxy)hept-6-ene-1,2-diol 
• 202338-89-4 [(E)-1-Cyano-5-methyl-6-(tetrahydro-pyran-2-yloxy)-hex-4-enyl]-phosphonic acid diethyl ester 
• 1609533-98-3 (2Z)-(4S)-4-benzyloxy-2-[(E)-4-methyl-5-[(tetrahydro-2H-pyran-2-yl)oxy]pent-3-enyl]octa-2,7-dienenitrile 

Downstream Products

• 1609534-03-3 ethyl (4aR,4bR,5S,8aS,10aR)-5-benzyloxy-1-chloro-8a-cyano-4a-methyl-8-methylene-2-oxoperhydrophenanthrene-1-carboxylate 
• 1609534-04-4 methyl (4aR,4bR,5S,8aS,10aR)-5-benzyloxy-1-chloro-8a-cyano-4a-methyl-8-methylene-2-oxoperhydrophenanthrene-1-carboxylate 
• 1609533-97-2 (4aR,4bR,5S,8aS)-5-benzyloxy-4a-methyl-8-methylene-2-oxo-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydrophenanthrene-8a-carbonitrile 
• 1609534-05-5 (1S,4aR,4bR,5S,8aS,10aR)-5-benzyloxy-1-chloro-4a-methyl-8-methylene-2-oxoperhydro-phenanthrene-8a-carbonitrile 
• 1609534-00-0 (2Z)-(4S)-4-benzyloxy-2-[(E)-5-bromo-4-methylpent-3-enyl]octa-2,7-dienenitrile 
• 1609534-01-1 ethyl (6E,10Z)-(12S)-12-benzyloxy-2-chloro-10-cyano-6-methyl-3-oxohexadeca-6,10,15-trienoate 
• 1609534-02-2 methyl (6E,10Z)-(12S)-12-benzyloxy-2-chloro-10-cyano-6-methyl-3-oxohexadeca-6,10,15-trienoate 

Relevant articles and documents

Divergent synthesis of pseudoenantiomers for ABC-ring moiety of steroids

Steroid family has various bioactivities and characteristic polycyclic structure. Although several synthetic methods have been reported, more efficient way is desired for medicinal chemistry. In this Letter, we synthesized pseudoenantiomers of tricyclic enones toward both enantiomers for ABC-ring moiety of steroids utilizing d-mannitol as a chiral source. The key steps are radical domino cyclization of polyalkenyl-β-keto ester into tricyclic keto ester and subsequent dealkoxycarbonylation.