1609554-41-7Relevant academic research and scientific papers
Alkene carboboration enabled by synergistic catalysis
Smith, Kevin B.,Logan, Kaitlyn M.,You, Wei,Brown, M. Kevin
supporting information, p. 12032 - 12036 (2015/03/31)
A synergistic Pd/Cu system for the coupling of alkenes, (Bpin)2 (pin=pinacolate), and aryl/vinyl bromides is disclosed. This method allows for the catalytic generation of secondary Csp3-Cu nucleophiles in situ and subsequent Pd-catalyzed cross-coupling. A synergistic Pd/Cu system for the coupling of alkenes, (Bpin)2 (pin=pinacolate), and aryl/vinyl bromides, was disclosed. This method allowed the catalytic generation of secondary Csp3-Cu nucleophiles in situ and subsequent Pd-catalyzed cross-coupling.
Arylboration of alkenes by cooperative palladium/copper catalysis
Semba, Kazuhiko,Nakao, Yoshiaki
supporting information, p. 7567 - 7570 (2014/06/10)
Arylboration of vinylarenes and methyl crotonate with aryl halides and bis(pinacolato)diboron by cooperative Pd/Cu catalysis has been developed, giving 2-boryl-1,1-diarylethanes and an α-aryl-β-boryl ester in a regioselective manner. The reaction is compatible with a variety of functionalities and amenable to be scaled-up to a gram scale with no detriment to the yield. A short synthesis of the biologically active compound CDP840 was performed using the present reaction as a key step.
