1609574-74-4Relevant academic research and scientific papers
Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma
Stephenson, Anthony A.,Cao, Sheng,Taggart, David J.,Vyavahare, Vinod P.,Suo, Zucai
, (2021)
Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug gemcitabine (2′,2′-difluorodeoxycytidine) for the treatment of hepatitis C v
