1609583-33-6

Basic information

• Product Name: 3-(phenylthio)imidazo[1,2-a]pyridine
• Synonyms: 3-(phenylthio)imidazo[1,2-a]pyridine
• CAS NO: 1609583-33-6
• Molecular Weight: 226.302
• Mol File: 1609583-33-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3-(phenylthio)imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(phenylthio)imidazo[1,2-a]pyridine(1609583-33-6)
• EPA Substance Registry System: 3-(phenylthio)imidazo[1,2-a]pyridine(1609583-33-6)

Safety Data

• Hazardous Substances Data: 1609583-33-6(Hazardous Substances Data)

Upstream product

• 274-76-0 imidazo[1,2-a]pyridine 
• 108-98-5 thiophenol 
• 98-80-6 phenylboronic acid 
• 873-55-2 sodium benzenesulfonate 
• 1212-08-4 S-Phenyl benzenethiosulfonate 

Relevant articles and documents

Copper-catalyzed three-component reaction of imidazo[1,2-a]pyridine with elemental sulfur and arylboronic acid to produce sulfenylimidazo[1,2-a]pyridines

In this work, an efficient copper-catalyzed three-component reaction for the synthesis of sulfenylimidazo[1,2-a]pyridines using elemental sulfur as the sulfenylating agents has been developed. The reaction could proceed smoothly with a high degree of functional group tolerance and provide the desired products in moderate to good yield.

Visible-light-induced regioselective sulfenylation of imidazopyridines with thiols under transition metal-free conditions

A metal-free visible-light-promoted regioselective C-3 sulfenylation of imidazo[1,2-a]pyridines and indoles using thiols has been developed via C(sp2)-H functionalization. This method provides direct access to a wide range of structurally diver

C3 Sulfenylation of N-Heteroarenes in Water under Catalyst-Free Conditions

A method for the catalyst-free C–H sulfenylation of imidazo[1,2-a]pyridines by using sulfonothioates as an odorless thioarylated reagent in aqueous medium was developed. This protocol was used for a variety of substituted imidazo[1,2-a]pyridines with broad functional-group tolerance and was extended to the sulfenylation of indoles and imidazothiazoles. The sulfonothioates were activated exclusively in aqueous medium rather than in an organic solvent, and the feasibility of the process for scale-up studies was demonstrated.