1609583-39-2

Upstream product

• 874765-01-2 2-(2-fluorophenyl)imidazo[1,2-a]pyridine 
• 873-55-2 sodium benzenesulfonate 
• 108-98-5 thiophenol 

Relevant academic research and scientific papers

Iodine-Mediated Difunctionalization of Imidazopyridines with Sodium Sulfinates: Synthesis of Sulfones and Sulfides

Novel iodine-induced sulfonylation and sulfenylation of imidazopyridines have been described using sodium sulfinates as the sulfur source. This strategy enables highly selective difunctionalization of imidazo[1,2-a]pyridine to access sulfones and sulfides in good yields. A wide range of substrates and functional groups were well-tolerated under optimized conditions. Moreover, control experiments have been conducted, indicating a radical pathway involved in the reaction mechanisms.

N-chlorosuccinimide-promoted regioselective sulfenylation of imidazoheterocycles at room temperature

Regioselective sulfenylation of imidazoheterocycles with thiophenols at room temperature is reported. Sulfenylation is promoted by N-chlorosuccinimide under metal-free conditions with a broad range of substrate scopes.