160961-35-3

Basic information

• Product Name: (R)-(+)-Nadifloxacin
• Synonyms: (R)-(+)-Nadifloxacin;1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-, (5R)- (9CI);1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-, (R)-;(4R)-1-Oxo-4α-methyl-5,6-dihydro-7-(4-hydroxypiperidino)-8-fluoro-4H-3a-aza-1H-phenalene-2-carboxylic acid;(5R)-9-Fluoro-6,7-dihydro-8-(4-hydroxypiperidino)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid
• CAS NO: 160961-35-3
• Molecular Formula: C19H21 F N2 O4
• Molecular Weight: 360.38
• Mol File: 160961-35-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-(+)-Nadifloxacin(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-Nadifloxacin(160961-35-3)
• EPA Substance Registry System: (R)-(+)-Nadifloxacin(160961-35-3)

Safety Data

• Hazardous Substances Data: 160961-35-3(Hazardous Substances Data)

Usage

General Description

(R)-(+)-Nadifloxacin is a topical fluoroquinolone antibiotic commonly used in the treatment of skin infections. It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus and Propionibacterium acnes, which are common pathogens in skin infections. The compound works by inhibiting bacterial DNA replication and repair, ultimately leading to the death of the bacteria. Additionally, it has anti-inflammatory properties, making it particularly effective in treating skin conditions such as acne vulgaris. (R)-(+)-Nadifloxacin is generally well-tolerated and has been shown to have minimal systemic absorption when applied topically, making it a safe and effective option for the treatment of various skin infections.