1609631-91-5Relevant academic research and scientific papers
The oxidative cross-coupling of benzonitriles with multiform substrates: A domino strategy inspired easy access to α-keto-imides
Kalmode, Hanuman P.,Vadagaonkar, Kamlesh S.,Chaskar, Atul C.
, p. 429 - 438 (2015)
An iodine-promoted highly efficient convergent synthesis of α-ketoimides from multiform substrates and benzonitriles through oxidative imidation reaction is described. This domino oxidative imidation process involves cleavage of C-H bond and construction of C-O and C-N bonds. This method could be a powerful compliment to the existing methods owing to its use of abundantly available starting materials and reagents.
Metal-free in situ sp3, sp2, and sp C-H functionalization and oxidative cross coupling with benzamidines hydrochloride: A promising approach for the synthesis of α-ketoimides
Kalmode, Hanuman P.,Vadagaonkar, Kamlesh S.,Chaskar, Atul C.
, p. 60316 - 60326 (2015/02/19)
A new metal-free tandem protocol for the synthesis of α-ketoimides via sp3, sp2, and sp C-H functionalization followed by oxidative cross coupling with benzamidines hydrochloride using catalytic iodine with TBHP in DMSO has been developed. A wide range of functional group tolerance, an inexpensive catalyst, operational simplicity and good to excellent yields of the products are the striking features of this method.
I2-catalyzed oxidative cross-coupling of methyl ketones and benzamidines hydrochloride: A facile access to α-ketoimides
Wu, Xia,Gao, Qinghe,Liu, Shan,Wu, Anxin
, p. 2888 - 2891 (2014/06/23)
An iodine-catalyzed oxidative cross-coupling of C-H/N-H has been demonstrated. This simple and efficient approach constructed α-ketoimides in good to excellent yields from methyl ketones and benzamidines hydrochloride under metal-free and peroxide-free co
