1609659-01-9
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Basic information
- Product Name: trans-Cyclooctene-maleimide
- Synonyms: TCO-PEG3-maleimide;trans-Cyclooctene-maleimide
- CAS NO:1609659-01-9
- Molecular Formula: C26H41N3O8
- Molecular Weight: 523.61904
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1609659-01-9.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C
- Solubility: N/A
- CAS DataBase Reference: trans-Cyclooctene-maleimide(CAS DataBase Reference)
- NIST Chemistry Reference: trans-Cyclooctene-maleimide(1609659-01-9)
- EPA Substance Registry System: trans-Cyclooctene-maleimide(1609659-01-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1609659-01-9(Hazardous Substances Data)
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1609659-01-9 Usage
Biochem/physiol Actions
Maleimide (thiol reactive) functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into thiol containing compounds or biomolecules. Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. The PEG spacer allows for increased water solubility; less aggregation and an increased distance between the thiol to be modified and the reactive alkene.Check Digit Verification of cas no
The CAS Registry Mumber 1609659-01-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,9,6,5 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1609659-01:
(9*1)+(8*6)+(7*0)+(6*9)+(5*6)+(4*5)+(3*9)+(2*0)+(1*1)=189
189 % 10 = 9
So 1609659-01-9 is a valid CAS Registry Number.
1609659-01-9Upstream product
1609659-01-9Downstream Products
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trans-Cyclooctene-maleimide
