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4-Bromo-2,6-difluoroiodobenzene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 160976-02-3 Structure
  • Basic information

    1. Product Name: 4-Bromo-2,6-difluoroiodobenzene
    2. Synonyms: 4-BROMO-2,6 DIFLUORO-1-IODOBENZENE;4-BROMO-2,6-DIFLUOROIODOBENZENE;2,6-DIFLUORO-4-BROMOIODOBENZENE;1-BROMO-3,5-DIFLUORO-4-IODOBENZENE;Bromodifluoroiodobenzene;5-Bromo-1,3-difluoro-2-iodobenzene
    3. CAS NO:160976-02-3
    4. Molecular Formula: C6H2BrF2I
    5. Molecular Weight: 318.89
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 160976-02-3.mol
  • Chemical Properties

    1. Melting Point: 40-41°C
    2. Boiling Point: 236.057 °C at 760 mmHg
    3. Flash Point: 96.564 °C
    4. Appearance: /
    5. Density: 2.343 g/cm3
    6. Vapor Pressure: 0.0742mmHg at 25°C
    7. Refractive Index: 1.604
    8. Storage Temp.: Room temperature.
    9. Solubility: N/A
    10. CAS DataBase Reference: 4-Bromo-2,6-difluoroiodobenzene(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-Bromo-2,6-difluoroiodobenzene(160976-02-3)
    12. EPA Substance Registry System: 4-Bromo-2,6-difluoroiodobenzene(160976-02-3)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 160976-02-3(Hazardous Substances Data)

160976-02-3 Usage

Chemical Properties

Off-white to light brown solid

Check Digit Verification of cas no

The CAS Registry Mumber 160976-02-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,9,7 and 6 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160976-02:
(8*1)+(7*6)+(6*0)+(5*9)+(4*7)+(3*6)+(2*0)+(1*2)=143
143 % 10 = 3
So 160976-02-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H2BrF2I/c7-3-1-4(8)6(10)5(9)2-3/h1-2H

160976-02-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Bromo-2,6-difluoroiodobenzene

1.2 Other means of identification

Product number -
Other names 5-bromo-1,3-difluoro-2-iodobenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160976-02-3 SDS

160976-02-3Upstream product

160976-02-3Relevant articles and documents

Utilising Sodium-Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C?H and C?F Bond Activations

Maddock, Lewis C. H.,Nixon, Tracy,Kennedy, Alan R.,Probert, Michael R.,Clegg, William,Hevia, Eva

supporting information, p. 187 - 191 (2017/12/07)

Pairing iron bis(amide) Fe(HMDS)2 with Na(HMDS) to form new sodium ferrate base [(dioxane)0.5?NaFe(HMDS)3] (1) enables regioselective mono and di-ferration (via direct Fe?H exchange) of a wide range of fluoroaromatic substrates under mild reaction conditions. Trapping of several ferrated intermediates has provided key insight into how synchronised Na/Fe cooperation operates in these transformations. Furthermore, using excess 1 at 80 °C switches on a remarkable cascade process inducing the collective twofold C?H/threefold C?F bond activations, where each C?H bond is transformed to a C?Fe bond whereas each C?F bond is transformed into a C?N bond.

Directed magnesiation of polyhaloaromatics using the tetramethylpiperidylmagnesium reagents TMP2Mg×2 LiCl and TMPMgCl×LiCl

Unsinn, Andreas,Rohbogner, Christoph J.,Knochel, Paul

supporting information, p. 1553 - 1560 (2013/06/27)

A convenient and efficient functionalization of polyhaloaromatics via regioselective magnesiation has been developed. Starting from simple, inexpensive but structurally challenging arenes, metallation by magnesium amide bases was achieved under mild conditions. The desired Grignard reagents were stable towards aryne formation, were obtained in good yields within short reaction times and could be reacted with a variety of typical electrophiles, providing attractive, functionalized building blocks in good to excellent yields. As an application we have prepared the antimicrobial natural product 2,6-dichloro-3-phenethylphenol isolated from the New Zealand liverwort Riccardia marginata. This synthesis involves a mixed bimetallic compound prepared via metallation of a phenylboronic acid pinacol ester derivative and subsequent selective cross-coupling. Copyright

N-(4-biphenylmethyl)imidazoles as potential therapeutics for the treatment of prostate cancer: Metabolic robustness due to fluorine substitution?

Leroux, Frederic,Hutschenreuter, Tilman U.,Charriere, Celine,Scopelliti, Rosario,Hartmann, Rolf W.

, p. 2671 - 2686 (2007/10/03)

3,3′,5,5′- And 2,2′,6,6′-tetrafluoro-substituted 1-[(1,1′-biphenyl]-4-yl)methyl]-1H-imidazoles were synthesized as inhibitors of 17α-hydroxylase-C17,20-lyase (P450 17, CYP 17). P450 17 is the key enzyme of androgen biosynthesis. Its inhibition is a novel

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