1609959-99-0

Basic information

• Product Name: N-methyl N-p-tolylsulfinylmethyl carbamic acid tert-butyl ester
• Synonyms: N-methyl N-p-tolylsulfinylmethyl carbamic acid tert-butyl ester
• CAS NO: 1609959-99-0
• Molecular Weight: 283.392
• Mol File: 1609959-99-0.mol

Chemical Properties

• CAS DataBase Reference: N-methyl N-p-tolylsulfinylmethyl carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl N-p-tolylsulfinylmethyl carbamic acid tert-butyl ester(1609959-99-0)
• EPA Substance Registry System: N-methyl N-p-tolylsulfinylmethyl carbamic acid tert-butyl ester(1609959-99-0)

Safety Data

• Hazardous Substances Data: 1609959-99-0(Hazardous Substances Data)

Upstream product

• 7541-17-5 tert-butyl N,N-dimethylcarbamate 
• 672-78-6 methyl p-toluene sulfinate 

Downstream Products

• 16066-84-5 N-(tert-butoxycarbonyl)methylamine 

Relevant articles and documents

On the synthesis of α-amino sulfoxides

A synthetic study on the preparation of N-Boc α-amino sulfoxides has revealed an unexpected instability which is believed to be due to α-elimination of the sulfoxide to give an iminium ion. Full synthetic details are reported on two main synthetic routes: lithiation and sulfinate trapping of N-Boc heterocycles and oxidation of N-Boc α-amino sulfides. Six novel α-amino sulfoxides were successfully prepared and isolated. It is speculated that four other α-amino sulfoxides were synthesised but could not be isolated due to their propensity to α-eliminate the sulfoxide. Ultimately, a stable, cyclic N-Boc α-amino sulfoxide was prepared and this successful synthesis relied on the α-amino sulfoxide being part of a bicyclic [3.1.0] fused ring system that could not undergo α-elimination of the sulfoxide. the Partner Organisations 2014.