1610032-21-7

Basic information

• Product Name: C₂₈H₂₇F₃N₂
• Synonyms: C₂₈H₂₇F₃N₂
• CAS NO: 1610032-21-7
• Molecular Weight: 448.531
• Mol File: 1610032-21-7.mol

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₇F₃N₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₇F₃N₂(1610032-21-7)
• EPA Substance Registry System: C₂₈H₂₇F₃N₂(1610032-21-7)

Safety Data

• Hazardous Substances Data: 1610032-21-7(Hazardous Substances Data)

Upstream product

• 705-31-7 4-trifluoromethylphenylacetylene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 693-13-0 diisopropyl-carbodiimide 

Relevant articles and documents

Cleavage of the C=N bond in carbodiimides via release of high ring strain: A new strategy for the selective synthesis of 2-aminoaryl alkynyl imines

A novel pattern of the cleavage and reorganization of C=N bond in the multicomponent reaction (MCR) of terminal alkynes or haloalkynes, carbodiimides, and benzynes is achieved for the first time to construct efficiently 2-aminoaryl alkynyl imines. The selective formation and ring-opening of the azetine intermediate with the high ring strain is essential for this reaction. Further transformation of 2-aminoaryl alkynyl imines via the Cu-catalyzed cycloisomerization is explored to provide steroselectively the bi-, tri-, and tetracyclic fused pyrrolines. A novel pattern in the cleavage and reorganization of the C=N bond in the multicomponent reaction of terminal alkynes or haloalkynes, carbodiimides, and benzynes is achieved for the first time to construct efficiently 2-aminoaryl alkynyl imines. The selective formation and ring-opening of the azetine intermediate with high ring strain is essential for this reaction (see scheme; Tf=trifluoromethanesulfonyl, TMS=trimethylsilyl). Copyright