1610048-85-5Relevant articles and documents
Synthesis of a cluster-forming sialylthio-d-galactose fullerene conjugate and evaluation of its interaction with influenza virus hemagglutinin and neuraminidase
Tollas, Szilvia,Bereczki, Ilona,Borbás, Anikó,Batta, Gyula,Vanderlinden, Evelien,Naesens, Lieve,Herczegh, Pál
, p. 2420 - 2423 (2014)
In order to obtain self assembling, multivalent ligand for influenza virus hemagglutinin α-N-acetylneuraminyl-(2-6)-d-galactopyranose has been synthesized and bonded to a water soluble fullerene derivative using 1,3-dipolar cycloaddition click reaction. The aggregating amphiphilic compound did not inhibit the influenza virus hemagglutinin, but it proved to be an inhibitor of its neuraminidase with a 50% inhibitory concentration of 81 μM.