1610342-20-5

Basic information

• Product Name: C₂₂H₂₀O₄
• CAS NO: 1610342-20-5
• Molecular Weight: 348.398
• Mol File: 1610342-20-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₀O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₀O₄(1610342-20-5)
• EPA Substance Registry System: C₂₂H₂₀O₄(1610342-20-5)

Safety Data

• Hazardous Substances Data: 1610342-20-5(Hazardous Substances Data)

Upstream product

• 15875-51-1 2-(4-methyl-benzylidene)-indan-1,3-dione 
• 111-30-8 Glutaraldehyde 

Relevant articles and documents

Organocatalytic synthesis of substituted spirocyclohexane carbaldehydes via [4 + 2] annulation strategy between 2-arylideneindane-1,3-diones and glutaraldehyde

An organocatalytic domino reaction between 2-arylideneindane-1,3-diones and glutaraldehyde has been devised that gives functionalized spirocyclohexane carbaldehydes with an all-carbon quaternary center. The reaction proceeds through a Michael/Aldol sequence in good-to-high chemical yields and with high levels of stereoselectivity (up to >95:5 dr and 99% ee) in the presence of the α,α-l-diphenylprolinol trimethylsilyl ether 3 (20 mol %) and DIPEA (20 mol %) in ether at 0 °C.