1610344-92-7

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 1610347-46-0 (1R,2R)-1-amino-4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-2-ol 
• 1610347-63-1 4-methyl-1-phenyl-3-(quinuclidin-3-yloxy)-1H-pyrazol-5-amine 
• 148967-82-2 3,3-dimethyl-1a,2,3,7b-tetrahydronaphtho[1,2-b]oxirene 
• 2733-79-1 1,2-dihydro-1,1-dimethylnaphthalene 
• 53952-18-4 4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-ol 
• 2979-69-3 3,4-dihydro-4,4-dimethyl-1(2H)-naphthalenone 

Relevant academic research and scientific papers

BICYCLIC UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN

Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.