1610359-24-4

Upstream product

• 179899-07-1 4-fluoro-2-methoxyphenylboronic acid 
• 884494-49-9 2-chloro-5-fluoro-4-iodopyridine 
• 1602486-03-2 2-chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridine 
• 354-38-1 2,2,2-trifluoroacetamide 
• 1602486-12-3 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{6-fluoro-4-[(methylsulfanyl)methyl]pyridin-2-yl}pyridin-2-amine 
• 1602486-11-2 6-fluoro-4-[(methylsulfanyl)methyl]pyridin-2-amine 
• 1393566-26-1 4-(chloromethyl)-6-fluoropyridin-2-amine 
• 1602486-10-1 (2-amino-6-fluoropyridin-4-yl)methanol 
• 1006299-98-4 2,6-difluoro-4-hydroxymethylpyridine 

Downstream Products

• 1610358-85-4 (rac)-5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{6-fluoro-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine 
• 1610358-87-6 (rac)-2,2,2-trifluoro-N-{[(2-fluoro-6-{[5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl]amino}pyridin-4-yl)methyl](methyl)oxido-λ⁶-sulfanylidene}acetamide 

Relevant academic research and scientific papers

5-FLUORO-N-(PYRIDIN-2-YL)PYRIDIN-2-AMINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP

The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).