1610610-03-1Relevant articles and documents
Ionic tagged DABCO grafted on magnetic nanoparticles: A water-compatible catalyst for the aqueous aza-Michael addition of amines to α,β- unsaturated amides
Ying, Anguo,Liu, Shuo,Ni, Yuxiang,Qiu, Fangli,Xu, Songlin,Tang, Wenyuan
, p. 2115 - 2125 (2014)
Ionic tagged 1,4-Diazabicyclo[2.2.2]octane (DABCO) grafted on magnetic nanoparticles (MNPs) was prepared and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), vibrating sample magnetometry (VSM) and thermal gravimetric analysis (TGA). The resulting magnetic solid supported DABCO catalyst with an ionic moiety was efficient for aza-Michael addition of aliphatic amines to various α,β-unsaturated amides in water at room temperature, affording the desired products in good to excellent yields. Gratifyingly, the catalyst could be readily recovered by an external magnet and reused ten times without any significant loss of activity. The Royal Society of Chemistry 2014.
DABCO-based ionic liquids: Recyclable catalysts for aza-michael addition of α,β-unsaturated amides under solvent-free conditions
Ying, Anguo,Li, Zhifeng,Yang, Jianguo,Liu, Shuo,Xu, Songlin,Yan, Hua,Wu, Chenglin
, p. 6510 - 6516 (2014)
An array of novel 1,4-diazobicyclo[2.2.2]octane (DABCO) based ionic liquids were developed and used as recyclable catalysts for the aza-Michael addition at room temperature without any organic solvent. [DABCO-PDO][OAc] was found to be the most efficient catalyst, and the amount of catalyst was only 10 mol %. Various amines reacted with a wide range of α,β-unsaturated amides, smoothly affording target products in good to excellent yields within hours. Moreover, the catalyst could be reused up to eight times, still maintaining a high catalytic activity. Finally, a plausible mechanism was proposed. FTIR and computational chemistry were used to verify the catalytic mechanism.
[CH3COO]: Efficient and recyclable catalyst for aza-Michael addition of α, β-unsaturated compounds and amines under solvent-free conditions
Gao, Xiaochong,Gao, Ruichang
, p. 9101 - 9112 (2015)
The recyclable ionic liquid [ADPQ][CH3COO] has been used as catalyst for aza-Michael addition of amines to α, β-unsaturated compounds to produce β-amino compounds. The reactions were complete in a few hours with high yields. The ionic liquid can be recycled and reused six times without noticeable decrease of catalytic activity.
