161068-68-4Relevant academic research and scientific papers
One-pot synthesis of the naturally occurring dimeric carbazole alkaloid murranimbine and its analogue
Chakraborty, Mumu,Mukhopadhyay, Sibabrata
, p. 3732 - 3735 (2010)
Murranimbine, a naturally occurring dimeric carbazole alkaloid, isolated from the root bark of Murraya euchrestfolia was synthesized in one step by the application of Lewis acid (BF3-Et2O) on its monomer girinimbine. A new dimer of koenidine was also synthesized following the same procedure. Structures of these dimeric carbazole alkaloids were determined by detailed spectral analysis.
A direct FeCl3-catalyzed cross-coupling and cyclization reactions: A new approach to the construction of functionalized pyrano[3,2-a]carbazole derivatives
Tan, Siow-Ping,Ahmad, Kartini,Nafiah, Mohd Azlan
, p. 4805 - 4810 (2017)
The FeCl3-catalyzed cross-coupling through a sequential C?N and C?C bond-forming via tandem C?H and N?H bonds functionalization represents a novel method for the formation of dimeric carbazole derivatives. This approach provides a novel dimeric carbazole, namely murrabicine (4), from murrayacine (1). Following the same procedure, a cycloadduct (6) has been achieved due to different substitution pattern at the pyran ring of the mahanimbine (3). This strategy opens up an efficient and direct route to the formation of biologically important pyrano[3,2-a]carbazole alkaloids.
