161068-69-5Relevant academic research and scientific papers
Synthesis of 5-(3-indolyl)oxazole natural products. Structure revision of Almazole D
Miyake, Fumiko,Hashimoto, Michinao,Tonsiengsom, Sorasaree,Yakushijin, Kenichi,Horne, David A.
experimental part, p. 4888 - 4893 (2010/08/06)
The synthesis and utility of β-oxotryptamine and β-oxytryptophan ester synthons provide a convenient entry to 5-(3-indolyl)oxazole natural products leading to a structure revision of almazole D.
Iminophosphorane-based preparation of 2,5-disubstituted oxazole derivatives: Synthesis of the marine alkaloid almazole C
Fresneda, Pilar M.,Casta?eda, Marta,Blug, Mathias,Molina, Pedro
, p. 324 - 326 (2007/10/03)
A four-steps synthesis (32% overall yield) of marine alkaloid almazole C isolated from the red seaweed Haraldiophylum sp. is described. The key step, construction of the central 2,5-disubstituted oxazole ring is based on the aza-Wittig reaction of the imi
Almazole C, a new indole alkaloid bearing an unusually 2,5-disubstituted oxazole moiety, and its putative biogenetic peptidic precursors, from a Senegalese delesseriacean seaweed
Guella,Mancini,N'Diaye,Pietra
, p. 1999 - 2006 (2007/10/02)
From product isolation and biomimetic synthesis - which also establishes absolute configurations - the known oxazole alkaloids almazoles A ((+)-1) and B ((+)-2) seem to arise in a Senegalese delesseriacean seaweed from, in sequence, the new modified pepti
