1610702-82-3Relevant academic research and scientific papers
The first carbonylation of perfluoroorganic compounds: The reactions of perfluorobenzocyclobutene and its perfluoroalkyl and pentafluorophenyl derivatives with CO in SbF5 medium
Zonov, Yaroslav V.,Karpov, Victor M.,Platonov, Vyacheslav E.
, p. 71 - 77 (2014/05/20)
Carbonylation of polyfluorinated benzocyclobutenes with CO in an SbF 5 medium readily proceeds at room temperature and atmospheric pressure and it is followed by four-membered ring transformations. Perfluorinated benzocyclobutene, 3- and 4-methyl-benzocyclobutenes add two CO molecules to form, after ring opening and following heterocyclization, isochromene derivatives. Hydrolysis of the reaction mixtures gives corresponding 4-carboxy-1H-isochromenes and 2-(carboxymethyl)benzoic acids. The carbonylation of perfluorinated 1-methyl-, 1-ethyl- and 1-isopropyl-benzocyclobutene gives salts of 2-(2-methylphenyl)alk-2-enoyl cations and the corresponding acids after hydrolysis of the latters. Perfluoro-1-phenylbenzocyclobutene in the reaction with CO-SbF5 transforms into a salt of perfluro-4-phenylisochromenyl cation, its hydrolysis gives perfluro-4-phenylisochromen-1-one.
