161085-74-1Relevant academic research and scientific papers
Efficient and stereoselective synthesis of 3'-deoxy 3'-C-branched-chain substituted thymidine
Sanghvi,Bharadwaj,Debart,De Mesmaeker
, p. 1163 - 1166 (1994)
In this report, we provide for the first time a facile, efficient, and stereoselective synthesis of 1-[5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-3-C-formyl-β-D-erythro-p entofuranosyl]thymine (12), using an intermolecular radical C-C bond formation reacti
Synthesis of 3′-C-substituted thymidine derivatives by free-radical techniques: scope and limitations
Horton, Derek,Chen, Kuangmin,No, Zaesung,Lee, Howard C.
, p. 259 - 267 (2007/10/03)
The scope and limitations of radical-mediated 3′-C-substitution of pyrimidine nucleosides was evaluated with 5′-O-(tert-butyldimethylsilyl)thymidine or its tert-butyldiphenylsilyl analogue having thionoester or thionoamide groups at O-3′, including (methy
Nucleoside homodimerisation by cross metathesis
Batoux, Nathalie,Benhaddou-Zerrouki, Rachida,Bressolier, Philippe,Granet, Robert,Laumont, Géraldine,Aubertin, Anne-Marie,Krausz, Pierre
, p. 1491 - 1493 (2007/10/03)
The cross metathesis of 3′-allylic analogues of thymidine, 2′-deoxyuridine and 2′-deoxycytidine is used to obtain nucleoside dimers, in which an unsaturated hydrocarbon chain links the 3′ positions of the sugar moieties. The biological activity on HIV inf
