1610871-13-0

Basic information

• Product Name: 1,7-dimethyl-2,3-diphenyl-1H-indole
• Synonyms: 1,7-dimethyl-2,3-diphenyl-1H-indole
• CAS NO: 1610871-13-0
• Molecular Weight: 297.4
• Mol File: 1610871-13-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,7-dimethyl-2,3-diphenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-dimethyl-2,3-diphenyl-1H-indole(1610871-13-0)
• EPA Substance Registry System: 1,7-dimethyl-2,3-diphenyl-1H-indole(1610871-13-0)

Safety Data

• Hazardous Substances Data: 1610871-13-0(Hazardous Substances Data)

Upstream product

• 6852-47-7 N,N-dimethyl-N-(2'-methylphenyl)amine N-oxide 
• 501-65-5 diphenyl acetylene 
• 1610870-85-3 2-isobutylidene-1-methyl-1-(2-methylphenyl)hydrazine 
• 70757-77-6 N-methyl-N-(o-methylphenyl)hydrazine 

Relevant articles and documents

Co(III)-Catalyzed, Internal and Terminal Alkyne-Compatible Synthesis of Indoles

A Co(III)-catalyzed, internal and terminal alkyne-compatible indole synthesis protocol is reported herein. The N-amino (hydrazine) group imparts distinct, diverse reactivity patterns for directed C-H functionalization/cyclization reactions. Notable synthetic features include regioselectivity for a meta-substituted arylhydrazine, regioselectivity for a chain-branched terminal alkyne, formal incorporation of an acetylenic unit through C2-desilylation on a C2-silylated indole derivative, formal inversion of regioselectivity through consecutive C3-derivatization and C2-desilylation processes, and formal bond migration for a linear-chain terminal alkyne.

Rhodium(III)-catalyzed synthesis of indoles from 1-alkylidene-2- arylhydrazines and alkynes via C-H and N-N bond cleavages

1-Alkylidene-2-arylhydrazines undergo annulative coupling with internal alkynes in the presence of a rhodium(III) catalyst and a copper(II) salt. The reaction proceeds through cleavage of the C-H and N-N bonds of hydrazines to afford 1,2,3-trisubstituted indole derivatives.