1610881-94-1

Basic information

• Product Name: (Z)-3-(2-methoxybenzylidene)-2-(quinolin-8-yl)isoindolin-1-one
• Synonyms: (Z)-3-(2-methoxybenzylidene)-2-(quinolin-8-yl)isoindolin-1-one
• CAS NO: 1610881-94-1
• Molecular Weight: 378.43
• Mol File: 1610881-94-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-3-(2-methoxybenzylidene)-2-(quinolin-8-yl)isoindolin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-(2-methoxybenzylidene)-2-(quinolin-8-yl)isoindolin-1-one(1610881-94-1)
• EPA Substance Registry System: (Z)-3-(2-methoxybenzylidene)-2-(quinolin-8-yl)isoindolin-1-one(1610881-94-1)

Safety Data

• Hazardous Substances Data: 1610881-94-1(Hazardous Substances Data)

Upstream product

• 33757-48-1 N-quinolin-8-yl-benzamide 
• 767-91-9 1-ethynyl-2-methoxybenzene 

Relevant articles and documents

Copper-mediated tandem oxidative C(sp2)-H/C(sp)-H alkynylation and annulation of arenes with terminal alkynes

The copper-mediated tandem oxidative C(sp2)-H/C(sp)-H cross-coupling and intramolecular annulation of arenes with terminal alkynes has been developed, which offers a highly efficient approach to the 3-methyleneisoindolin-1-one scaffold. In this oxidative coupling process, Cu(OAc)2 acts as both the promoter and the terminal oxidant. This protocol features a wide substrate scope; high functional group tolerance; exclusive chemo-, regio-, and stereoselectivity; and simple, easily available, and inexpensive reaction system. The transformation has demonstrated for the first time that Cu(OAc)2 can be renewable after undergoing an oxidative reaction.