1610893-03-2Relevant academic research and scientific papers
New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII
Ceruso, Mariangela,Bragagni, Marco,Alothman, Zeid,Osman, Sameh M.,Supuran, Claudiu T.
, p. 430 - 434 (2015)
New benzenesulfonamides incorporating water solubilizing moieties were synthesized using N-α-acetyl-l-lysine or γ-aminobutyric acid as scaffolds followed by the conversion of their terminal amino group to the guanidine one. Their inhibition activity was a
Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase
Ceruso, Mariangela,Del Prete, Sonia,Alothman, Zeid,Osman, Sameh M.,Scozzafava, Andrea,Capasso, Clemente,Supuran, Claudiu T.
, p. 4006 - 4010 (2014/09/03)
New benzenesulfonamides incorporating GABA or N-α-acetyl-l-lysine scaffolds as well as guanidine functionalities as water solubilizing moieties were obtained, using 4-aminoethyl/methyl-benzenesulfonamide and metanilamide/sulfanilamide as zinc-binding moti
