1610922-24-1

Basic information

• Product Name: C₂₃H₂₉NO₆S
• Synonyms: C₂₃H₂₉NO₆S
• CAS NO: 1610922-24-1
• Molecular Weight: 447.552
• Mol File: 1610922-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₉NO₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₉NO₆S(1610922-24-1)
• EPA Substance Registry System: C₂₃H₂₉NO₆S(1610922-24-1)

Safety Data

• Hazardous Substances Data: 1610922-24-1(Hazardous Substances Data)

Upstream product

• 55750-53-3 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid 

Relevant articles and documents

TRIOXACARCINS, TRIOXACARCIN-ANTIBODY CONJUGATES, AND USES THEREOF

Provided herein are trioxacarcin-antibody drug conjugates of Formula (A): and pharmaceutically acceptable salts thereof, comprising at least one instance of the group - L1 -(A-L2 )a-B attached thereto, wherein a is an integer between 1 and 10, inclusive, L1 is absent or is a linking group, A is a moiety formed from the reaction of two complimentary groups (X and Y), L2 is absent or is another linking group, and B is an antibody or antibody fragment. Also provided are methods of preparing these antibody-drug conjugates, pharmaceutically acceptable compositions thereof, and methods of their use and treatment. Further provided are precursors to the trioxacarcin-antibody drug conjugates, novel trioxacarcins without an antibody conjugated thereto, pharmaceutical compositions thereof, and methods of their use and treatment.